A research team led by Prof Zheng Ying in the Institute of Chinese Medical Sciences (ICMS) at the University of Macau (UM) has discovered the prolonged circulation and elimination mechanism of crosslinked polymeric micelles in zebrafish model, providing scientific support and guidance for the rational design and optimisation of injected nanomedicines. Their finding can help researchers improve the efficacy of nanomedicines and reduce toxic and side effects. The study has been published in Biomaterials, a top international journal in the field.