A research team, led by Prof Lu Jiahong in the Institute of Chinese Medical Sciences at the University of Macau (UM), and another research team, led by Prof Li Min in the School of Chinese Medicine at Hong Kong Baptist University (HKBU), have revealed the molecular mechanism by which the autophagy-related gene NRBF2 (Nuclear Receptor Binding Factor 2) regulates the maturation of autophagosomes and the pathological protein degradation in Alzheimer’s disease, which suggests a potential new therapeutic strategy for treating the disease. The study has been published online by the authoritative international academic journal Autophagy.